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Discovering functional sequences with RELICS, an analysis method for CRISPR screens

CRISPR screens are a powerful technology for the identification of genome sequences that affect cellular phenotypes such as gene expression, survival, and proliferation. By targeting non-coding sequences for perturbation, CRISPR screens have the potential to systematically discover novel functional...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Fiaux, Patrick C., Chen, Hsiuyi V., Chen, Poshen B., Chen, Aaron R., McVicker, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521704/
https://ncbi.nlm.nih.gov/pubmed/32936799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008194
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