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Discovering functional sequences with RELICS, an analysis method for CRISPR screens
CRISPR screens are a powerful technology for the identification of genome sequences that affect cellular phenotypes such as gene expression, survival, and proliferation. By targeting non-coding sequences for perturbation, CRISPR screens have the potential to systematically discover novel functional...
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| Publié dans: | PLoS Comput Biol |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521704/ https://ncbi.nlm.nih.gov/pubmed/32936799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008194 |
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