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Next-Generation Sequencing of Genome-Wide CRISPR Screens

Genome-wide functional genomic screens utilizing the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system have proven to be a powerful tool for systematic genomic perturbation in mammalian cells and provide an alternative to previous screens utilizing RNA interference techn...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Yau, Edwin H., Rana, Tariq M.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089254/
https://ncbi.nlm.nih.gov/pubmed/29224076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7514-3_13
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