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Efficiently identifying genome-wide changes with next-generation sequencing data

We propose a new and effective statistical framework for identifying genome-wide differential changes in epigenetic marks with ChIP-seq data or gene expression with mRNA-seq data, and we develop a new software tool EpiCenter that can efficiently perform data analysis. The key features of our framewo...

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Autors principals: Huang, Weichun, Umbach, David M., Vincent Jordan, Nicole, Abell, Amy N., Johnson, Gary L., Li, Leping
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201882/
https://ncbi.nlm.nih.gov/pubmed/21803788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr592
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