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Discovery of novel choline acetyltransferase inhibitors using structure-based virtual screening

Alzheimer disease and related dementias are major challenges, demanding urgent needs for earliest possible diagnosis to optimize the success rate in finding effective therapeutic interventions. Mounting solid scientific premises point at the core acetylcholine-biosynthesizing cholinergic enzyme, ChA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Kumar, Rajnish, Kumar, Amit, Långström, Bengt, Darreh-Shori, Taher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701137/
https://ncbi.nlm.nih.gov/pubmed/29176551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16033-w
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