Llwytho...

Orchestration of DNA damage checkpoint dynamics across the human cell cycle

Although molecular mechanisms that prompt cell cycle arrest in response to DNA damage have been elucidated, the systems-level properties of DNA damage checkpoints are not understood. Here, using time-lapse microscopy and simulations that model the cell cycle as a series of Poisson processes, we char...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Syst
Prif Awduron: Chao, Hui Xiao, Poovey, Cere E., Privette, Ashley A., Grant, Gavin D., Chao, Hui Yan, Cook, Jeanette G., Purvis, Jeremy E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700845/
https://ncbi.nlm.nih.gov/pubmed/29102360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.09.015
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!