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Orchestration of DNA damage checkpoint dynamics across the human cell cycle
Although molecular mechanisms that prompt cell cycle arrest in response to DNA damage have been elucidated, the systems-level properties of DNA damage checkpoints are not understood. Here, using time-lapse microscopy and simulations that model the cell cycle as a series of Poisson processes, we char...
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| Publicado no: | Cell Syst |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5700845/ https://ncbi.nlm.nih.gov/pubmed/29102360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.09.015 |
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