Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

To maintain tissue homeostasis, cells transition between cell cycle quiescence and proliferation. An essential G1 process is minichromosome maintenance complex (MCM) loading at DNA replication origins to prepare for S phase, known as origin licensing. A p53-dependent origin licensing checkpoint norm...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Matson, Jacob Peter, House, Amy M., Grant, Gavin D., Wu, Huaitong, Perez, Joanna, Cook, Jeanette Gowen
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605788/
https://ncbi.nlm.nih.gov/pubmed/31186278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902143
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