Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

To maintain tissue homeostasis, cells transition between cell cycle quiescence and proliferation. An essential G1 process is minichromosome maintenance complex (MCM) loading at DNA replication origins to prepare for S phase, known as origin licensing. A p53-dependent origin licensing checkpoint norm...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Matson, Jacob Peter, House, Amy M., Grant, Gavin D., Wu, Huaitong, Perez, Joanna, Cook, Jeanette Gowen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605788/
https://ncbi.nlm.nih.gov/pubmed/31186278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902143
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