Intrinsic checkpoint deficiency during cell cycle re-entry from quiescence

To maintain tissue homeostasis, cells transition between cell cycle quiescence and proliferation. An essential G1 process is minichromosome maintenance complex (MCM) loading at DNA replication origins to prepare for S phase, known as origin licensing. A p53-dependent origin licensing checkpoint norm...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Matson, Jacob Peter, House, Amy M., Grant, Gavin D., Wu, Huaitong, Perez, Joanna, Cook, Jeanette Gowen
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605788/
https://ncbi.nlm.nih.gov/pubmed/31186278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902143
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