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PD-L1 Promotes Self-Renewal and Tumorigenicity of Malignant Melanoma Initiating Cells

Recent studies have indicated that therapeutic antibodies targeting PD-L1 show remarkable efficacy in clinical trials in multiple tumors and that a melanoma cell-intrinsic PD-1: PD-L1 axis promotes tumor growth. However, few studies have shown tumor-intrinsic PD-L1 effects in malignant melanoma init...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zheng, Fang, Dang, Jianzhong, Zha, Hui, Zhang, Bingyu, Lin, Ming, Cheng, Fanjun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700500/
https://ncbi.nlm.nih.gov/pubmed/29250533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1293201
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