SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of...

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Detalhes bibliográficos
Main Authors: Santini, R, Pietrobono, S, Pandolfi, S, Montagnani, V, D'Amico, M, Penachioni, J Y, Vinci, M C, Borgognoni, L, Stecca, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180644/
https://ncbi.nlm.nih.gov/pubmed/24681955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.71
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