SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma

BACKGROUND: Head and neck squamous cell carcinomas (HNSCCs) display cellular heterogeneity and contain cancer stem cells (CSCs). Sex-determining region Y [SRY]-box (SOX)2 is an important regulator of embryonic stem cell fate and is aberrantly expressed in several types of human tumours. Nonetheless,...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Lee, S H, Oh, S-Y, Do, S I, Lee, H J, Kang, H J, Rho, Y S, Bae, W J, Lim, Y C
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260038/
https://ncbi.nlm.nih.gov/pubmed/25321191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.528
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