SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of...

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Bibliographic Details
Main Authors:	Santini, R, Pietrobono, S, Pandolfi, S, Montagnani, V, D'Amico, M, Penachioni, J Y, Vinci, M C, Borgognoni, L, Stecca, B
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2014
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4180644/ https://ncbi.nlm.nih.gov/pubmed/24681955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.71
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SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

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