SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells

Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of...

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Bibliografiske detaljer
Main Authors: Santini, R, Pietrobono, S, Pandolfi, S, Montagnani, V, D'Amico, M, Penachioni, J Y, Vinci, M C, Borgognoni, L, Stecca, B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180644/
https://ncbi.nlm.nih.gov/pubmed/24681955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.71
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