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Cancer stem cell vaccination with PD-L1 and CTLA-4 blockades enhances the eradication of melanoma stem cells in a mouse tumor model

Immune checkpoint inhibitors and monoclonal antibodies re-invigorate cancer immunotherapy. However, these immunotherapies only benefit a subset of patients. We previously reported that ALDH(high) tumor cells were highly enriched for cancer stem cells (CSCs), and ALDH(high) CSC lysate-pulsed dendriti...

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Bibliografiske detaljer
Udgivet i:J Immunother
Main Authors: Zheng, Fang, Dang, Jianzhong, Zhang, Hongyu, Xu, Fangzhou, Ba, Diandian, Zhang, Bingyu, Cheng, Fanjun, Chang, Alfred E., Wicha, Max S., Li, Qiao
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128768/
https://ncbi.nlm.nih.gov/pubmed/30063587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000242
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