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Cancer stem cell vaccination with PD-L1 and CTLA-4 blockades enhances the eradication of melanoma stem cells in a mouse tumor model
Immune checkpoint inhibitors and monoclonal antibodies re-invigorate cancer immunotherapy. However, these immunotherapies only benefit a subset of patients. We previously reported that ALDH(high) tumor cells were highly enriched for cancer stem cells (CSCs), and ALDH(high) CSC lysate-pulsed dendriti...
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| Publicado no: | J Immunother |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128768/ https://ncbi.nlm.nih.gov/pubmed/30063587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000242 |
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