Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats

Quantitative whole-body autoradiography was used to assess the distribution and tissue penetration of isavuconazole in rats following single and repeated oral-dose administration of radiolabeled isavuconazonium sulfate, the prodrug of isavuconazole. Following a single-dose administration of radiolab...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Schmitt-Hoffmann, Anne-Hortense, Kato, Kota, Townsend, Robert, Potchoiba, Michael J., Hope, William W., Andes, David, Spickermann, Jochen, Schneidkraut, Marlowe J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700325/
https://ncbi.nlm.nih.gov/pubmed/28971866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01292-17
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