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Population Pharmacokinetics of Isavuconazole in Subjects with Mild or Moderate Hepatic Impairment

Isavuconazole, administered as the prodrug isavuconazonium sulfate, was recently approved by the U.S. Food and Drug Administration and the European Medicines Agency for the treatment of adults with invasive aspergillosis and mucormycosis. The objective of this analysis was to develop a population ph...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Desai, Amit, Schmitt-Hoffmann, Anne-Hortense, Mujais, Salim, Townsend, Robert
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862513/
https://ncbi.nlm.nih.gov/pubmed/26953193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02942-15
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