Achievement of clinical isavuconazole blood concentrations in transplant recipients with isavuconazonium sulphate capsules administered via enteral feeding tube

BACKGROUND: Isavuconazole is a triazole antifungal available in IV and capsule formulation. Prescribing information states that capsules should not be chewed, crushed, dissolved or opened because the drug was not studied in this manner. However, considering the pharmacokinetics of the capsules, we t...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: McCreary, Erin K, Nguyen, M Hong, Davis, Matthew R, Borlagdan, Jared, Shields, Ryan K, Anderson, Anthony D, Rivosecchi, Ryan M, Marini, Rachel V, Sacha, Lauren M, Silveira, Fernanda P, Andes, David R, Lepak, Alexander J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778376/
https://ncbi.nlm.nih.gov/pubmed/32710097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa274
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