Population Pharmacokinetics of Intravenous Isavuconazole in Solid-Organ Transplant Recipients

Isavuconazole (ISA) is a triazole antifungal with activity against yeasts and molds. We established a population pharmacokinetic (pop PK) model of intravenous (i.v.) ISA to identify covariates that affect pharmacokinetics, using plasma samples from solid-organ transplant (SOT) recipients receiving p...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Wu, Xuemei, Venkataramanan, Raman, Rivosecchi, Ryan M., Tang, Chenxiao, Marini, Rachel V., Shields, Ryan K., Clancy, Cornelius J., Nguyen, M. Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985716/
https://ncbi.nlm.nih.gov/pubmed/31767725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01728-19
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