Effects of Isavuconazole on the Plasma Concentrations of Tacrolimus among Solid-Organ Transplant Patients

We evaluated the interaction between isavuconazole and tacrolimus among 55 organ transplant recipients. After isavuconazole discontinuation, the tacrolimus concentration/dose ratio normalized by weight (C/D) was reduced by 16%. Liver transplant recipients experienced the largest C/D reduction. A 1.3...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Rivosecchi, Ryan M., Clancy, Cornelius J., Shields, Ryan K., Ensor, Christopher R., Shullo, Michael A., Falcione, Bonnie A., Venkataramanan, Raman, Nguyen, M. Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571345/
https://ncbi.nlm.nih.gov/pubmed/28674051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00970-17
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