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Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster

DNA replication depends on primase, the specialised polymerase responsible for synthesis of the RNA primers that are elongated by the replicative DNA polymerases. In eukaryotic and archaeal replication, primase is a heterodimer of two subunits, PriS and PriL. Recently, a third primase subunit named...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Holzer, Sandro, Yan, Jiangyu, Kilkenny, Mairi L., Bell, Stephen D., Pellegrini, Luca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700102/
https://ncbi.nlm.nih.gov/pubmed/29167441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01707-w
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