Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine

[Image: see text] Nucleoside analogues are widely used in clinical practice as chemotherapy drugs. Arabinose nucleoside derivatives such as fludarabine are effective in the treatment of patients with acute and chronic leukemias and non-Hodgkin’s lymphomas. Although nucleoside analogues are generally...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Chem Biol
Egile Nagusiak: Holzer, Sandro, Rzechorzek, Neil J., Short, Isobel R., Jenkyn-Bedford, Michael, Pellegrini, Luca, Kilkenny, Mairi L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6757278/
https://ncbi.nlm.nih.gov/pubmed/31479243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00367
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