Baseline and Breakthrough Resistance Mutations in HCV Patients Failing DAAs

Sustained virologic response rates have increased dramatically following direct acting antiviral (DAA) therapy in chronic HCV infection. However, resistance-associated substitutions (RASs) may occur either prior to DAA or following drug exposure. The aim of this study was to determine RASs in DAA tr...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Paolucci, Stefania, Premoli, Marta, Novati, Stefano, Gulminetti, Roberto, Maserati, Renato, Barbarini, Giorgio, Sacchi, Paolo, Piralla, Antonio, Sassera, Davide, De Marco, Leone, Girello, Alessia, Mondelli, Mario U., Baldanti, Fausto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700050/
https://ncbi.nlm.nih.gov/pubmed/29167469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15987-1
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