Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients

BACKGROUND: Direct-acting antiviral (DAA) agents target HCV proteins; some of these have already been approved for the treatment of HCV infection, while others are in development. However, selection of DAA-resistant viral variants may hamper treatment. The aim of this study was to illustrate potenti...

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Detalhes bibliográficos
Main Authors: Paolucci, Stefania, Fiorina, Loretta, Mariani, Bianca, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Bruno, Raffaele, Baldanti, Fausto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878512/
https://ncbi.nlm.nih.gov/pubmed/24341898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-355
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