Baseline Amino Acid Substitutions in the NS5A ISDR and PKR Binding Domain of Hepatitis C and Different Fibrosis Levels and Levels of Development of Hepatocellular Carcinoma in Patients Treated with DAAs

Variations in the interferon sensitivity-determining region (ISDR) within the NS5A region were related to the development of hepatocellular carcinoma (HCC) in patients infected with hepatitis C virus (HCV). The aim of the study was to investigate a relationship between ISDR/PKR substitutions and the...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Paolucci, Stefania, Piralla, Antonio, Novazzi, Federica, Fratini, Alice, Maserati, Renato, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Sacchi, Paolo, De Silvestri, Annalisa, Baldanti, Fausto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150791/
https://ncbi.nlm.nih.gov/pubmed/32106574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12030255
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