Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients

BACKGROUND: Protease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development. RESULTS: The aims of this study were to illustrate natural polymorphisms in the HCV protease and measure the frequency of PI resistance mutations in different HCV gen...

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Détails bibliographiques
Auteurs principaux: Paolucci, Stefania, Fiorina, Loretta, Piralla, Antonio, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Sacchi, Paolo, Gatti, Marta, Dossena, Luca, Baldanti, Fausto
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493344/
https://ncbi.nlm.nih.gov/pubmed/23095680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-245
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