Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation

A group of homologous nucleic acid modification enzymes called Dnmt2, Trdmt1, Pmt1, DnmA, and Ehmet in different model organisms catalyze the transfer of a methyl group from the cofactor S-adenosyl-methionine (SAM) to the carbon-5 of cytosine residues. Originally considered as DNA MTases, these enzy...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Jeltsch, Albert, Ehrenhofer-Murray, Ann, Jurkowski, Tomasz P., Lyko, Frank, Reuter, Gunter, Ankri, Serge, Nellen, Wolfgang, Schaefer, Matthias, Helm, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699548/
https://ncbi.nlm.nih.gov/pubmed/27232191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1191737
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