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Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism
Although their amino acid sequences and structure closely resemble DNA methyltransferases, Dnmt2 proteins were recently shown by Goll and colleagues to function as RNA methyltransferases transferring a methyl group to the C5 position of C38 in tRNA(Asp). We observe that human DNMT2 methylates tRNA i...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2491481/ https://ncbi.nlm.nih.gov/pubmed/18567810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.970408 |
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