The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA

The amino acid sequence of Dnmt2 is very similar to the catalytic domains of bacterial and eukaryotic DNA-(cytosine 5)-methyltransferases, but it efficiently catalyzes tRNA methylation, while its DNA methyltransferase activity is the subject of controversial reports with rates varying between zero a...

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Vydáno v:RNA Biol
Hlavní autoři: Kaiser, Steffen, Jurkowski, Tomasz P., Kellner, Stefanie, Schneider, Dirk, Jeltsch, Albert, Helm, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699543/
https://ncbi.nlm.nih.gov/pubmed/27819523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1236170
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