Defects in Recombination Activity Caused by Somatic and Germline Mutations in the Multimerization/BRCA2 Binding Region of Human RAD51 Protein

The human RAD51 recombinase possesses DNA pairing and strand exchange activities that are essential for the error-free, homology-directed repair of DNA double-strand breaks. The recombination activities of RAD51 are activated upon its assembly into presynaptic filaments on single-stranded DNA at res...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:DNA Repair (Amst)
Autores principales: Silva, Michelle C., Bryan, Katie E., Morrical, Milagros D., Averill, April M., Dragon, Julie, Wiegmans, Adrian P., Morrical, Scott W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699509/
https://ncbi.nlm.nih.gov/pubmed/29100040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.10.008
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares