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RAD51 Variant Proteins from Human Lung and Kidney Tumors Exhibit DNA Strand Exchange Defects
In human cells, error-free repair of DNA double-strand breaks requires the DNA pairing and strand exchange activities of RAD51 recombinase. Activation of RAD51 recombination activities requires the assembly of RAD51 presynaptic filaments on the single-stranded DNA that forms at resected DSB ends. Mu...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884548/ https://ncbi.nlm.nih.gov/pubmed/27153211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.02.008 |
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