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How does the exosite of rhomboid protease affect substrate processing and inhibition?
Rhomboid proteases constitute a family of intramembrane serine proteases ubiquitous in all forms of life. They differ in many aspects from their soluble counterparts. We applied molecular dynamics (MD) computational approach to address several challenging issues regarding their catalytic mechanism:...
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| Veröffentlicht in: | Protein Sci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699488/ https://ncbi.nlm.nih.gov/pubmed/28884847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3294 |
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