Chargement en cours...

Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy

The 20S proteasome core particle (20S CP) plays an integral role in cellular homeostasis by degrading proteins no longer required for function. The process is, in part, controlled via gating residues localized to the ends of the heptameric barrel-like CP structure that occlude substrate entry pores,...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Huang, Rui, Pérez, Felipe, Kay, Lewis E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699070/
https://ncbi.nlm.nih.gov/pubmed/29087330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712297114
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!