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Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy
The 20S proteasome core particle (20S CP) plays an integral role in cellular homeostasis by degrading proteins no longer required for function. The process is, in part, controlled via gating residues localized to the ends of the heptameric barrel-like CP structure that occlude substrate entry pores,...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699070/ https://ncbi.nlm.nih.gov/pubmed/29087330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712297114 |
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