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On the damage done to the structure of the Thermoplasma acidophilum proteasome by electron radiation

It has long been known that proteins are damaged when they are exposed to the electron beam in an electron microscope. Here we show that exposure to electrons under cryo‐EM conditions leads to a small change in the quaternary structure of the Thermoplasma acidophilum proteasome, and that backbones a...

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Détails bibliographiques
Publié dans:Protein Sci
Auteurs principaux: Wang, Jimin, Liu, Zheng, Crabtree, Robert H., Frank, Joachim, Moore, Peter B.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237698/
https://ncbi.nlm.nih.gov/pubmed/30242932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3511
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