The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial

AIMS: Increasing evidence indicates that the ATP‐generating enzyme creatine kinase (CK) is involved in hypertension. CK rapidly regenerates ATP from creatine phosphate and ADP. Recently, it has been shown that beta‐guanidinopropionic acid (GPA), a kidney‐synthesized creatine analogue and competitive...

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Detaylı Bibliyografya
Yayımlandı:Br J Clin Pharmacol
Asıl Yazarlar: Karamat, Fares A., Horjus, Deborah L., Haan, Yentl C., van der Woude, Lisa, Schaap, Marianne C., Oudman, Inge, van Montfrans, Gert A., Nieuwland, Rienk, Salomons, Gajja S., Clark, Joseph F., Brewster, Lizzy M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Clinical Trials
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698587/
https://ncbi.nlm.nih.gov/pubmed/28795416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13390
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