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The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial

AIMS: Increasing evidence indicates that the ATP‐generating enzyme creatine kinase (CK) is involved in hypertension. CK rapidly regenerates ATP from creatine phosphate and ADP. Recently, it has been shown that beta‐guanidinopropionic acid (GPA), a kidney‐synthesized creatine analogue and competitive...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Karamat, Fares A., Horjus, Deborah L., Haan, Yentl C., van der Woude, Lisa, Schaap, Marianne C., Oudman, Inge, van Montfrans, Gert A., Nieuwland, Rienk, Salomons, Gajja S., Clark, Joseph F., Brewster, Lizzy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698587/
https://ncbi.nlm.nih.gov/pubmed/28795416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13390
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