The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial

AIMS: Increasing evidence indicates that the ATP‐generating enzyme creatine kinase (CK) is involved in hypertension. CK rapidly regenerates ATP from creatine phosphate and ADP. Recently, it has been shown that beta‐guanidinopropionic acid (GPA), a kidney‐synthesized creatine analogue and competitive...

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Bibliografische gegevens
Gepubliceerd in:Br J Clin Pharmacol
Hoofdauteurs: Karamat, Fares A., Horjus, Deborah L., Haan, Yentl C., van der Woude, Lisa, Schaap, Marianne C., Oudman, Inge, van Montfrans, Gert A., Nieuwland, Rienk, Salomons, Gajja S., Clark, Joseph F., Brewster, Lizzy M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Clinical Trials
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698587/
https://ncbi.nlm.nih.gov/pubmed/28795416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13390
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