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mDia1 senses both force and torque during F-actin filament polymerization
Formins, an important family of force-bearing actin-polymerizing factors, function as homodimers that bind with the barbed end of actin filaments through a ring-like structure assembled from dimerized FH2 domains. It has been hypothesized that force applied to formin may facilitate transition of the...
Guardat en:
| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698482/ https://ncbi.nlm.nih.gov/pubmed/29162803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01745-4 |
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