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Tropomyosin concentration but not formin nucleators mDia1 and mDia3 determines the level of tropomyosin incorporation into actin filaments

The majority of actin filaments in human cells exist as a co-polymer with tropomyosin, which determines the functionality of actin filaments in an isoform dependent manner. Tropomyosin isoforms are sorted to different actin filament populations and in yeast this process is determined by formins, how...

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Publicat a:Sci Rep
Autors principals: Meiring, Joyce C. M., Bryce, Nicole S., Niño, Jorge Luis Galeano, Gabriel, Antje, Tay, Szun S., Hardeman, Edna C., Biro, Maté, Gunning, Peter W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482184/
https://ncbi.nlm.nih.gov/pubmed/31019238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42977-2
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