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Biphasic Effect of Profilin Impacts the Formin mDia1 Force-Sensing Mechanism in Actin Polymerization

Formins are force-sensing proteins that regulate actin polymerization dynamics. Here, we applied stretching tension to individual actin filaments under the regulation of formin mDia1 to investigate the mechanical responses in actin polymerization dynamics. We found that the elongation of an actin fi...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Kubota, Hiroaki, Miyazaki, Makito, Ogawa, Taisaku, Shimozawa, Togo, Kinosita, Kazuhiko, Ishiwata, Shin’ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529311/
https://ncbi.nlm.nih.gov/pubmed/28746856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.012
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