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Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)
Inverted formin 2 (INF2) encodes a member of the diaphanous subfamily of formin proteins. Mutations in INF2 cause human kidney disease characterized by focal and segmental glomerulosclerosis. Disease-causing mutations occur only in the diaphanous inhibitory domain (DID), suggesting specific roles fo...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041098/ https://ncbi.nlm.nih.gov/pubmed/21278336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017010108 |
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