Biphasic Effect of Profilin Impacts the Formin mDia1 Force-Sensing Mechanism in Actin Polymerization

Formins are force-sensing proteins that regulate actin polymerization dynamics. Here, we applied stretching tension to individual actin filaments under the regulation of formin mDia1 to investigate the mechanical responses in actin polymerization dynamics. We found that the elongation of an actin fi...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Kubota, Hiroaki, Miyazaki, Makito, Ogawa, Taisaku, Shimozawa, Togo, Kinosita, Kazuhiko, Ishiwata, Shin’ichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2017
Onderwerpen:
Molecular Machines, Motors, and Nanoscale Biophysics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529311/
https://ncbi.nlm.nih.gov/pubmed/28746856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.012
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