Information processing in the NF-κB pathway

The NF-κB pathway is known to transmit merely 1 bit of information about stimulus level. We combined experimentation with mathematical modeling to elucidate how information about TNF concentration is turned into a binary decision. Using Kolmogorov-Smirnov distance, we quantified the cell’s ability t...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tudelska, Karolina, Markiewicz, Joanna, Kochańczyk, Marek, Czerkies, Maciej, Prus, Wiktor, Korwek, Zbigniew, Abdi, Ali, Błoński, Sławomir, Kaźmierczak, Bogdan, Lipniacki, Tomasz
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698458/
https://ncbi.nlm.nih.gov/pubmed/29162874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16166-y
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