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Importins promote high-frequency NF-κB oscillations increasing information channel capacity
BACKGROUND: Importins and exportins influence gene expression by enabling nucleocytoplasmic shuttling of transcription factors. A key transcription factor of innate immunity, NF-κB, is sequestered in the cytoplasm by its inhibitor, IκBα, which masks nuclear localization sequence of NF-κB. In respons...
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| 出版年: | Biol Direct |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106790/ https://ncbi.nlm.nih.gov/pubmed/27835978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-016-0164-z |
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