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Importins promote high-frequency NF-κB oscillations increasing information channel capacity
BACKGROUND: Importins and exportins influence gene expression by enabling nucleocytoplasmic shuttling of transcription factors. A key transcription factor of innate immunity, NF-κB, is sequestered in the cytoplasm by its inhibitor, IκBα, which masks nuclear localization sequence of NF-κB. In respons...
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| Publicado no: | Biol Direct |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106790/ https://ncbi.nlm.nih.gov/pubmed/27835978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-016-0164-z |
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