Characterizing a thermostable Cas9 for bacterial genome editing and silencing

CRISPR-Cas9-based genome engineering tools have revolutionized fundamental research and biotechnological exploitation of both eukaryotes and prokaryotes. However, the mesophilic nature of the established Cas9 systems does not allow for applications that require enhanced stability, including engineer...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Mougiakos, Ioannis, Mohanraju, Prarthana, Bosma, Elleke F., Vrouwe, Valentijn, Finger Bou, Max, Naduthodi, Mihris I. S., Gussak, Alex, Brinkman, Rudolf B. L., van Kranenburg, Richard, van der Oost, John
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698299/
https://ncbi.nlm.nih.gov/pubmed/29162801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01591-4
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