Abnormal CFTR Affects Glucagon Production by Islet α Cells in Cystic Fibrosis and Polycystic Ovarian Syndrome

Glucagon, produced by islet α cells, functions to increase blood glucose. Abnormal glucose levels are often seen in cystic fibrosis (CF), a systematic disease caused by mutations of the CF transmembrane conductance regulator (CFTR), and in polycystic ovarian syndrome (PCOS), an endocrine disorder fe...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Huang, Wen Qing, Guo, Jing Hui, Yuan, Chun, Cui, Yu Gui, Diao, Fei Yang, Yu, Mei Kuen, Liu, Jia Yin, Ruan, Ye Chun, Chan, Hsiao Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698272/
https://ncbi.nlm.nih.gov/pubmed/29204121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00835
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