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Cystic Fibrosis, CFTR, and Colorectal Cancer

Cystic fibrosis (CF), caused by biallelic inactivating mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, has recently been categorized as a familial colorectal cancer (CRC) syndrome. CF patients are highly susceptible to early, aggressive colorectal tumor development....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Scott, Patricia, Anderson, Kyle, Singhania, Mekhla, Cormier, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7215855/
https://ncbi.nlm.nih.gov/pubmed/32326161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21082891
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