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Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes
Cystic fibrosis (CF)-related diabetes (CFRD) is thought to result from beta-cell injury due in part to pancreas exocrine damage and lipofibrosis. CFRD pancreata exhibit reduced islet density and altered cellular composition. To investigate a possible etiology, we tested the hypothesis that such chan...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5722914/ https://ncbi.nlm.nih.gov/pubmed/29222447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17404-z |
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