Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet

Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevity. Yet, the complex pathogenesis of CFRD remains u...

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Publicado en:PLoS One
Main Authors: Di Fulvio, Mauricio, Bogdani, Marika, Velasco, Myrian, McMillen, Timothy S., Ridaura, Cecilia, Kelly, Lisa, Almutairi, Mohammed M., Kursan, Shams, Sajib, Abu A., Hiriart, Marcia, Aguilar-Bryan, Lydia
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710116/
https://ncbi.nlm.nih.gov/pubmed/33264332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242749
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