Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human islet

Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator (CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting ~50% of all CF patients, significantly influencing pulmonary function and longevity. Yet, the complex pathogenesis of CFRD remains u...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Di Fulvio, Mauricio, Bogdani, Marika, Velasco, Myrian, McMillen, Timothy S., Ridaura, Cecilia, Kelly, Lisa, Almutairi, Mohammed M., Kursan, Shams, Sajib, Abu A., Hiriart, Marcia, Aguilar-Bryan, Lydia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710116/
https://ncbi.nlm.nih.gov/pubmed/33264332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242749
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky