Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure

OBJECTIVE: Cystic fibrosis–related diabetes (CFRD) is a common complication of cystic fibrosis (CF), increasing patient morbidity and mortality. Poor understanding of CFRD pathogenesis limits the development of targeted therapies to treat and/or prevent the disease. The aim of this study was to eval...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Hull, Rebecca L., Gibson, Ronald L., McNamara, Sharon, Deutsch, Gail H., Fligner, Corinne L., Frevert, Charles W., Ramsey, Bonnie W., Sanda, Srinath
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Pathophysiology/Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5860832/
https://ncbi.nlm.nih.gov/pubmed/29437698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc17-1387
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