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SURVIVAL IN A BAD NEIGHBORHOOD: PANCREATIC ISLETS IN CYSTIC FIBROSIS

In cystic fibrosis (CF), ductal plugging and acinar loss result in rapid decline of exocrine pancreatic function. This destructive process results in remodeled islets, with only a modest reduction in insulin producing β cells. However, β-cell function is profoundly impaired, with decreased insulin r...

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Dades bibliogràfiques
Publicat a:J Endocrinol
Autors principals: Norris, Andrew W., Ode, Katie Larson, Merjaneh, Lina, Sanda, Srinath, Yi, Yaling, Sun, Xingshen, Engelhardt, John F., Hull, Rebecca L.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675675/
https://ncbi.nlm.nih.gov/pubmed/30759072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0468
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