SURVIVAL IN A BAD NEIGHBORHOOD: PANCREATIC ISLETS IN CYSTIC FIBROSIS

In cystic fibrosis (CF), ductal plugging and acinar loss result in rapid decline of exocrine pancreatic function. This destructive process results in remodeled islets, with only a modest reduction in insulin producing β cells. However, β-cell function is profoundly impaired, with decreased insulin r...

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Bibliographic Details
Published in:J Endocrinol
Main Authors: Norris, Andrew W., Ode, Katie Larson, Merjaneh, Lina, Sanda, Srinath, Yi, Yaling, Sun, Xingshen, Engelhardt, John F., Hull, Rebecca L.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675675/
https://ncbi.nlm.nih.gov/pubmed/30759072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-18-0468
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